Artificial Ovary Fertility Treatment Now Developed By Scientists

Leslie Hanson
July 5, 2018

Women who undergo cancer diagnosis and treatment would now be able to get their ovaries removed and frozen before they start the treatment.

Although the artificial ovaries have not been tested on humans, the scientists believe, in theory, the eggs would begin to mature and, in accordance with one's menstrual cycle, be released. By removing DNA from ovarian tissue cells, the method could also cut the risk of cancer re-occurring through an ovarian implant, since these cells don't contain the aberrant biological coding that would cause malignant growths.

"The artificial ovary will consist of a scaffold (originating from the woman's own tissue or from donated tissue) combined with her own follicles", Pors explained to CNN.

The research was presented at the annual meeting of the European Society of Human Reproduction and Embryology.

Professor Geeta Nargund, medical director of Create Fertility, told HuffPostUK it was an "exciting development which gives hope to young women with cancer ". Unlike ovarian tissues, follicles do not contain cancer cells.

The Danish team took the immature egg cells showed that they could survive on a structure made from stripping ovarian tissue of all its cells, leaving behind only its extracellular matrix.

A way to prevent such damage is to have an ovarian tissue transplant in which the parts or the entire ovary is removed and then frozen before the women undergo fertility harming treatments so that the frozen tissue can be put back at a later date.

But they said it might have advantages over other fertility treatments. This scaffold was then seeded with early-stage follicles.

As a proof-of-concept, Pors said it could offer a new strategy in fertility preservation without risk of cancer reoccurrence. "But it is certainly a promising approach". They are thrust into premature menopause, and although the use of hormone replacement therapy and their own cryopreserved eggs allows some of these women to become pregnant, their natural hormones and natural fertility will not be renewed.

The development achieved by researchers at the Rigshospitalet in Denmark, which could be available within three years, means women with malfunctioning ovaries can look forward to getting pregnant naturally.

For most patients, the process is said to be safe, yet certain tumors, for example, ovarian or leukemia, can attack the ovarian tissue as well. This portion could then be used later when the woman wants to conceive.

Other reports by Iphone Fresh

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